{"id":100603,"date":"2026-03-28T16:40:27","date_gmt":"2026-03-28T16:40:27","guid":{"rendered":"https:\/\/www.yakujihou.com\/kinousei\/?p=53008"},"modified":"2026-09-16T22:44:43","modified_gmt":"2026-09-16T13:44:43","slug":"100603","status":"publish","type":"merumaga","link":"https:\/\/www.yakujihou.com\/mailmagazines\/archive\/100603\/","title":{"rendered":"\u6a5f\u80fd\u6027\u8868\u793a\u6700\u65b0\u60c5\u5831\u00a0434\u53f7 \/\u3000\u6700\u8fd1\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u4e8b\u60c5"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u3053\u3093\u306b\u3061\u306f\u3002YDC\u306e\u30df\u30c3\u30b7\u30fc\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PRISMA2020\u4ee5\u964d\u306b\u306a\u3063\u3066\u304b\u3089\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3092\u5b9f\u65bd\u3057\u3066\u3044\u308bSR\u3082\u5c11\u3057\u5897\u3048\u3066\u304d\u305f\u3088\u3046\u306b\u601d\u3048<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u3059\u3002\u305d\u3053\u306b\u306f\u8272\u3005\u306a\u4e8b\u60c5\u304c\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3093\u304c\u3001\u57fa\u672c\u7684\u306b\u306f\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u5b9f\u65bd\u3057\u3066\u3044<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u308b\u65b9\u304c\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u3057\u3066\u306e\u4fe1\u983c\u6027\u304c\u9ad8\u307e\u308b\u306e\u3067\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u826f\u3044\u3053\u3068\u3060\u3068\u8a00\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3001\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3064\u3044\u3066\u306f\u3042\u308b\u7a0b\u5ea6\u306e\u77e5<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8b58\u304c\u306a\u3044\u3068\u3001\u6b63\u78ba\u306b\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u96e3\u3057\u304b\u3063\u305f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u308a\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u5e83\u544a\u306a\u3069\u3067\u4f7f\u304a\u3046\u3068\u3059\u308b\u3068\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8272\u3005\u306a\u6570\u5024\u304c\u51fa\u3066\u304d\u3066\u3001\u4f55\u3092\u793a\u3059\u3079\u304d\u306a\u306e\u304b\u308f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u304b\u3089\u306a\u3044\u3001\u3068\u3044\u3046\u4e8b\u3082\u3042\u308b\u3088\u3046\u3067\u3059\u3002\u305d\u3053\u3067\u4eca<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u56de\u306f\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u898b\u308b\u3068\u304d\u306e\u3001\u4ee3\u8868\u7684\u306a\u6570<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5024\u306b\u3064\u3044\u3066\u307e\u3068\u3081\u3066\u307f\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4ee5\u4e0b\u306fPRISMA2020\u306b\u5bfe\u5fdc\u3057\u305f\u6700\u8fd1\u306eSR\u304b\u3089\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306e\u4ee3\u8868\u7684\u306a\u6570\u5024\u3092\u62fe\u3063\u3066\u304d\u3066\u6574\u7406<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">K797<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">10m\u969c\u5bb3\u7269\u6b69\u884c\u30c6\u30b9\u30c8\uff08\u524d\u5f8c\u5dee\u5909\u5316\u7387\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MD\uff1a-11.41 % [95%CI\uff1a-16.54; -6.28]<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Heterogeneity\uff1aI2=0%; \u03c42(tau2)=0 p=0.53<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">K773<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a18\u61b6\u529b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SMD\uff1a0.103 [95%CI\uff1a0.037; 0.168]<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Heterogeneity\uff1aI2=55%; p=0.00<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">K771<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u4e2d\u9178\u5316LDL\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">SMD\uff1a-0.25 [95%CI\uff1a-0.39; -0.11]<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Heterogeneity\uff1aI2=0%; \u03c42(tau2)=0 p=0.64<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307e\u305a\u898b\u308b\u3079\u304d\u306fMD\u3068SMD\u3002MD\u306f\u5e73\u5747\u5dee\u306a\u306e\u3067\u3001<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">K797\u306e\u5834\u5408\u300110m\u969c\u5bb3\u7269\u6b69\u884c\u30c6\u30b9\u30c8\uff08\u524d\u5f8c\u5dee\u5909<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5316\u7387\uff09\u306b\u304a\u3044\u3066\u3001-11.41 %\u306e\u6539\u5584\u304c\u3042\u3063\u305f\u3001\u3068<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a00\u3048\u307e\u3059\u3002\u4e00\u65b9\u3001K773\u3084K771\u306fSMD\uff08\u6a19\u6e96\u5316\u5e73<\/p>\n\n\n\n<p 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